Definition: infiltration of many organ systems by mast cells with varied clinical manifestations that can include fever, weight loss, flushing, bronchospasm, rhinorrhea, palpitations, dyspnea, diarrhea, gastrointestinal bleeding, and hypotension.
Synonym(s): systemic mastocytosis
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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.