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dibucaine number

Pronunciation: dib'yu-kan num'ber

Definition: A test for differentiation of one of several forms of atypical pseudocholinesterases that are unable to inactivate succinylcholine at normal rates; based on the percentage of inhibition of the enzymes by dibucaine, normal enzyme has a DN of at least 75 and higher, heterozygous atypical enzyme has a DN of 40–70, and homozygous atypical enzyme has a DN of less than 20.

See Also: fluoride number

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.