- Reduction of the level of functioning.
- Displacement of a part downward or inward.
- A mental state or chronic mental disorder characterized by feelings of sadness, loneliness, despair, low self-esteem, and self-reproach; accompanying signs include psychomotor retardation (or less frequently agitation), withdrawal from social contact, and vegetative states such as loss of appetite and insomnia.
[L. depressio, fr. deprimo, to press down]
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Examples: glitazone, GI cocktail, etc.