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Pronunciation: de-jen'er-a'shun


  1. Deterioration; passing from a higher to a lower level or type.
  2. A worsening of mental, physical, or moral qualities.
  3. A retrogressive pathologic change in cells or tissues in consequence of which their functions are often impaired or destroyed; sometimes reversible; necrosis results in the early stages.

See: anterograde, retrograde

Synonym(s): retrograde metamorphosis

[L. degeneratio]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.