Enzymes catalyzing simple hydrolysis of C—NH2 bonds of purines, pyrimidines, and pterins, thus producing ammonia (usually named in terms of the substrate, guanine deaminases, adenosine deaminases, AMP deaminases, pterin deaminases); not generally used for deamination of noncyclic amides. Deaminases are distinguished from ammonia-lyases in that the latter produce an unsaturation at the point of NH3 removal.
Synonym(s): deaminating enzymes
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Examples: glitazone, GI cocktail, etc.