- A member of the subclass of hydrolases (EC class 3), especially of that subclass of esterases, lipases, lactonases, and hydrolases (EC subclass 3.1).
- Any enzyme catalyzing the hydrolytic cleavage of an acyl group (R—CO—) in an ester linkage; also includes enzymes cleaving amide linkages (EC subclass 3.5) and similar acyl compounds.
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Examples: glitazone, GI cocktail, etc.