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cytotoxic T-lymphocyte antigen-4

 

Definition: expressed by activated T cells. When synthesized as a soluble molecule fused to the Fc of IgG, it is used as a biologic therapy in rhematic diseases, because it blocks a costimulatory molecule on B lymphocytes.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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