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cytochrome b5 reductase

Pronunciation: si'to-krom re-duk'tas

Definition: A flavoenzyme catalyzing the reduction of two molecules of ferricytochrome b5 to two molecules of ferrocytochrome b5 at the expense of NADH; has a role in fatty acid desaturation; a deficiency can lead to hereditary methemoglobinemia (type I, only observed in erythrocyte cytosol; type II, deficiency in all tissues; type III, deficiency in all hematopoetic cells).

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.