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CYP 2E1

 

Definition: microsomal enzyme that participates in the oxidation of ethanol and acetaminophen. Inhibited by disulfiram and induced by ethanol and isoniazid (INH). Believed to be responsible for the hepatotoxic metabolite of acetaminophen.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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