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CYP 2C9

 

Definition: microsomal enzyme responsible for the oxidation of S-warfarin, phenytoin, and numerous NSAIDs. Inhibitors include azole antifungals (ketoconazole, itraconazole, metronidazole); induced by rifampin.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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