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Pronunciation: si'klo-pep'tid

Definition: One of a group of cyclic peptides that inhibit RNA polymerase and thus block protein synthesis. Used as topical antimicrobials, but toxic if ingested. Constituent in mushrooms that causes toxicity (amatoxin).

See Also: polymyxin, amatoxin

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.