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Cushing disease of the omentum

Pronunciation: kush'ing

Definition: central obesity in association with glucocorticoid excess, in which adipose stromal cells of the omental fat, but not of the subcutaneous tissue, can generate active cortisol from inactive cortisone. Patients have increased cortisol production and urinary cortisol excretion but no abnormality in the hypothalamico pituitary-adrenal axis.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.