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Medical Term:

Crooke hyaline change

Pronunciation: kruk

Definition: replacement of cytoplasmic granules of basophil cells of the anterior pituitary by homogeneous hyaline material; a characteristic finding in Cushing syndrome, but usually not present in the cells of a basophil adenoma.

Synonym(s): Crooke hyaline degeneration

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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