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Crooke hyaline change

Pronunciation: kruk

Definition: replacement of cytoplasmic granules of basophil cells of the anterior pituitary by homogeneous hyaline material; a characteristic finding in Cushing syndrome, but usually not present in the cells of a basophil adenoma.

Synonym(s): Crooke hyaline degeneration

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.