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corticobasal degeneration

 

Definition: a rare, progressive disease (considered by some a variant of Parkinson disease) involving both cerebral cortex and extrapyramidal structures; clinically manifest as disturbances of voluntary movements and rigidity; pathologic characteristics include degeneration of the cerebral cortex with balloon neurons and degeneration of the substantia nigra; apraxia, cortical sensory loss, myoclonus, and phantom limb syndrome have been reported.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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