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Coronaviridae

Pronunciation: ko-ro'na-vir'i-de

Definition: A family of single-stranded RNA-containing viruses with three or four major antigens corresponding to each of the major viral proteins; some cause upper respiratory tract infections in humans similar to the “common cold”; others cause animal infections (infectious avian bronchitis, swine encephalitis, mouse hepatitis, neonatal calf diarrhea, and others). The viruses resemble myxoviruses except for the petal-shaped projections that give an impression of the solar corona. Virions are 120–160 nm in diameter, enveloped and sensitive to ether. Nucleocapsids are thought to be of helical symmetry; they develop in cytoplasm and are enveloped by budding into cytoplasmic vesicles. Coronavirus and Torovirus are the only recognized genera.

[L. corona, garland, crown]

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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