Definition: toxoplasmosis apparently resulting from parasites in an infected mother being transmitted in utero to the fetus, observed as three syndromes: acute: most of the organs contain foci of necrosis in association with fever, jaundice, hydrocephaly, encephalomyelitis, pneumonitis, cutaneous rash, ophthalmic lesions, hepatomegaly, and splenomegaly; subacute: most of the lesions are partly healed or calcified, but those in the brain and eye seem to remain active, inasmuch as chorioretinitis is observed in more than 80% of diseased infants; and chronic: usually not recognized during the newborn period, but chorioretinitis and cerebral lesions may be detected weeks to years later.
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