congenital dyserythropoietic anemia
Definition: a group of anemias characterized by ineffective erythropoiesis, bone marrow erythroblastic multinuclearity, and secondary hemochromatosis. Three types are described: type I [MIM224120], macrocytic, megaloblastic anemia with erythroblastic internuclear chromatin bridges; type II, [MIM*224100], normoblastic anemia with multinucleated erythroblasts; type III, macrocytic anemia with erythroblastic multinuclearity and gigantoblasts [MIM*105600]. Both types I and II are autosomal recessively inherited, type III is of autosomal dominant inheritance.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.