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competitive binding assay

 

Definition: general term for an assay in which a substance competes for labeled versus unlabeled ligand; following separation of free and bound ligand, the concentration of unlabeled ligand is inversely proportional to the amount of labeled bound ligand. Values are compared with known standards.

Synonym(s): displacement analysis, saturation analysis

See Also: enzyme-linked immunosorbent assay, radioreceptor assay, immunoassay, enzyme-multiplied immunoassay technique, radioimmunoassay

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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