The peeled dried fruit of Citrullus colcynthis (family Cucurbitaceae), an herb that grows on the sandy shores of the Mediterranean, resembling somewhat the watermelon plant; formerly widely used as a cathartic and laxative.
Synonym(s): bitter apple
[G. kolokynthe, the round gourd or pumpkin]
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Examples: glitazone, GI cocktail, etc.