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Pronunciation: ko-laps'in

Definition: A secreted protein found in bird and rat embryos that collapses the growth cone of axons originating in spinal ganglia. Thought to pattern sensory projections from the ganglia by selectively repelling certain axons so that they terminate dorsally.

Synonym(s): semaphorin III

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.