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collagen disease

 

Definition: a group of generalized diseases affecting connective tissue and frequently characterized by fibrinoid necrosis or vasculitis; in some collagen diseases, auto-immunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; “collagen” was once synonymous with “connective tissue” rather than describing a specific fibrinous protein in that tissue.

See Also: connective-tissue disease

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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