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Pronunciation: ko'ag-yu-la'shun


  1. Clotting; the process of changing from a liquid to a solid, said especially of blood (blood coagulation). In vertebrates, blood coagulation is a result of cascade regulation from fibrin.
  2. A clot or coagulum.
  3. Transformation of a sol into a gel or semisolid mass, the coagulation of the white of an egg by means of boiling. In any colloidal suspension, the disperse phase is greatly reduced via coagulation, thereby leading to a complete or partial separation of the coagulant; usually an irreversible phenomenon unless the basic nature of the substance is chemically altered.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.