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coactivator

Pronunciation: ko-ak'ti-va-tor

Definition: A type of nuclear proteins that participate in the potentiation of transcription of genes that are responsive to ligand-dependent transcription factors. They belong to several families, including the p160 coactivators and the CBP/p300 molecules.

[co- + activator]

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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