Definition: A type of nuclear proteins that participate in the potentiation of transcription of genes that are responsive to ligand-dependent transcription factors. They belong to several families, including the p160 coactivators and the CBP/p300 molecules.
[co- + activator]
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.