Skip to Content

class switch

Pronunciation: klas switch

Definition: Before activation, a B cell may only produce antigen-specific IgM but after appropriate immunomodulatory signals, the B cell may class switch and produce other antibody isotypes, such as IgA and IgG. All antibodies produced from the same clone will have the same antigen specificity, even though the immunoglobulin isotypes may be different.

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.