Definition: the level of invasion of primary malignant melanoma of the skin; limited to the epidermis, I; into the underlying papillary dermis, II; to the junction of the papillary and reticular dermis, III; into the reticular dermis, IV; into the subcutaneous fat, V. The prognosis is worse with each successive deeper level of invasion.
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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.