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Pronunciation: sik-lo-fil'inz

Definition: Intracellular proteins associated with heat shock proteins and other molecules (glucocorticoid receptor). Ciclophilins mediate immunosuppressive actions of antirejection drugs (ciclosporin and FK-506).

[ciclosporin + G. philia, affinity, attaction, + -in]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.