chronic inflammatory demyelinating polyneuropathy
Definition: an uncommon, acquired, demyelinating sensorimotor polyneuropathy, clinically characterized by insidious onset, slow evolution, (either steady progression or stepwise), and chronic course; symmetric weakness is a predominant symptom, often involving proximal leg muscles, accompanied by paresthesias, but not pain; CSF examination shows elevated protein, whereas electrodiagnostic studies reveal evidence of a demyelinating process, primarily conduction slowing rather than block; sometimes responds to prednisone.
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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.