Skip to Content
Medical Term:

chronic adrenocortical insufficiency


Definition: adrenocortical insufficiency usually as the result of idiopathic atrophy or destruction of both adrenal glands by tuberculosis, an autoimmune process, or other diseases; characterized by fatigue, decreased blood pressure, weight loss, increased melanin pigmentation of the skin and mucous membranes, anorexia, and nausea or vomiting; without appropriate replacement therapy, it can progress to acute adrenocortical insufficiency.

Synonym(s): Addison disease, addisonian syndrome, hyposupradrenalism, morbus Addisonii

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.