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chloride shift


Definition: when CO2 enters the blood from the tissues, it passes into the red blood cells and is converted by carbonate dehydratase to bicarbonate (HCO3-); HCO3- ion passes out into the plasma whereas Cl- migrates into the red blood cells. Reverse changes occur in the lungs when CO2 is eliminated from the blood.

Synonym(s): Hamburger phenomenon

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.