Skip to Content

chloride shift


Definition: when CO2 enters the blood from the tissues, it passes into the red blood cells and is converted by carbonate dehydratase to bicarbonate (HCO3-); HCO3- ion passes out into the plasma whereas Cl- migrates into the red blood cells. Reverse changes occur in the lungs when CO2 is eliminated from the blood.

Synonym(s): Hamburger phenomenon

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.