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Pronunciation: klor'am-fen'i-kol

Definition: An antibiotic originally obtained from Streptomyces venezuelae. It is effective against several pathogenic microorganisms. A serious reaction resulting in marrow damage with agranulocytosis or aplastic anemia may occur. Gray syndrome may occur in newborns because glucuronosyltransferase, needed to metabolize the drug, is lacking.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.