Definition: a variable is said to have a chi-square distribution with K degrees of freedom if it is distributed like the sum of the squares of K independent random variables, each of which has a normal (gaussian) distribution with mean zero and variance one. The chi-square distribution is the basis for many variations of the chi-square(d) test, perhaps the most widely used test for statistical significance in biology and medicine.
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Examples: glitazone, GI cocktail, etc.