Definition: Complex formation involving a metal ion and two or more polar groupings of a single molecule; in heme, the Fe2+ ion is chelated by the porphyrin ring. Chelation can be used to remove an ion from participation in biologic reactions, as in the chelation of Ca2+ of blood by EDTA, which thus acts as an anticoagulant.
[G. chēlē, claw]
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.
Search Stedman's Medical Dictionary
Examples: glitazone, GI cocktail, etc.