cervical intraepithelial neoplasia
Definition: dysplastic changes beginning at the squamocolumnar junction in the uterine cervix that may be precursors of squamous cell carcinoma: grade 1, mild dysplasia involving the lower one third or less of the epithelial thickness; grade 2, moderate dysplasia with one third to two thirds involvement; grade 3, severe dysplasia or carcinoma in situ, with two thirds to full-thickness involvement.
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Examples: glitazone, GI cocktail, etc.