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Definition: a type III transmembrane protein found on platelets, megakaryocytes, monocytes, pre-B cells, eosinophils, basophils, and activated T cells; plays a role in signal transduction leading to platelet activation and aggregation; expressed in some T-cell acute lymphocytic leukemias and some acute nonlymphocytic leukemias.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.