Definition: a type III transmembrane protein found on platelets, megakaryocytes, monocytes, pre-B cells, eosinophils, basophils, and activated T cells; plays a role in signal transduction leading to platelet activation and aggregation; expressed in some T-cell acute lymphocytic leukemias and some acute nonlymphocytic leukemias.
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Examples: glitazone, GI cocktail, etc.