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Definition: a membrane protein present on some germinal-center B cells, mitogen-activated B cells, and monocytes that serves as a B-cell activator; expressed in anaplastic large cell lymphomas, on Reed-Sternberg cells, and on Epstein Barr virus–transformed B cells.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.