Definition: a type I transmembrane protein present on monocytes, macrophages, osteoclasts, mast cells, cytoplasmic granules, activated platelets, and large lymphocytes; expressed in neuroma Schwann cells, in nerves undergoing wallerian degeneration, in myeloid cell tumors, and in anaplastic lymphomas and epithelial tumors.
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Examples: glitazone, GI cocktail, etc.