Definition: a type I transmembrane protein present on B cells, T cells, neutrophils, thymocytes, monocytes, eosinophils, erythroid and myeloid progenitor cells, and natural killer cells; functions as a peripheral lymph node homing receptor and facilitates binding to endothelium at inflammatory sites; found on many malignant leukocytes.
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Examples: glitazone, GI cocktail, etc.