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Definition: a glycosylphosphatidylinositol-anchored membrane protein present on many hemopoietic cells, vascular endothelium, epithelial cells, and placenta that inhibits membrane complement attack and may be involved in T-cell signal transduction; absent or defective in paroxysmal nocturnal hemoglobinuria.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.