Definition: altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring.
Synonym(s): signet ring cells
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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.