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cartilage oligomeric matrix protein


Definition: a member of the trombospondin gene family, it is expressed at high levels in the matrix of chondrocytes. Mutations in the cartilage oligomeric matrix protein gene, COMP, [MIM*600310], result in pseudoachondroplasia and multiple epiphysial dysplasia.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.