Definition: disorder characterized by hundreds to thousands of precancerous colonic polyps beginning at about age 16 years. Colon cancer predisposition syndrome (familial polyposis coli, Peutz-Jeghers syndrome, juvenile polyposis syndrome). Rare disease affecting 1 in 25,000 people; either familial or sporadic; characterized by development of dozens to thousands of hamartomatous (benign) polyps in the stomach.
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Examples: glitazone, GI cocktail, etc.