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calcineurin

Pronunciation: kal′sē-nyūr′in

Definition: A calcium-dependent serine-threonine phosphatase involved in T-cell signaling transcription; the target of cyclosporine immunosuppression; the reaction cascade in which it resides is referred to as the calcineurin pathway.

[calcium + G. neuron, nerve, + -in]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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