Skip to Content

cachectin

Pronunciation: ka-kek′tin

Definition: A polypeptide cytokine, produced by endotoxin-activated macrophages, which has the ability to modulate adipocyte metabolism, lyse tumor cells in vitro, and induce hemorrhagic necrosis of certain transplantable tumors in vivo.

Synonym(s): tumor necrosis factor

[G. kakos, bad, + hexis, condition of body]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

Hide