Definition: a sequence of nucleotides found in a conserved region of DNA located “upstream” (5′ direction) of the start points of eukaryotic transcription units; specific transcription factors appear to associate with it; found in many promoters at −75 bp with the consensus sequence GG(T/C)CAATCT. It is believed to determine the efficiency of transcription.
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Examples: glitazone, GI cocktail, etc.