Definition: a selective chromosome banding stain used in human cytogenetics, employing Giemsa stain after most of the DNA is denatured or extracted by treatment with alkali, acid, salt, or heat; only heterochromatic regions close to the centromeres and rich in satellite DNA stain, except for the Y chromosome its long arm usually stains throughout.
Synonym(s): centromere banding stain
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Examples: glitazone, GI cocktail, etc.