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butyrate:CoA ligase

Pronunciation: byū′ti-rāt lī′gās

Definition: Fatty acid thiokinase (medium chain), a ligase forming acyl-CoA's from medium-chain fatty acids and CoA with the conversion of ATP to AMP and pyrophosphate. A key step in the activation of fatty acids.

Synonym(s): acyl-activating enzyme2, butyryl-CoA synthetase, octanoyl-CoA synthetase

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.