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BRCA1 gene

 

Definition: a tumor suppressor gene on chromosome 17 at locus 17q21, isolated in 1994; carriers of germline mutations in BRCA1 are predisposed to develop both breast and ovarian cancer.

See Also: BRCA2 gene, carcinoma of the breast

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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