Definition: a solution of glacial acetic acid, formalin, and picric acid; useful for soft and delicate tissues (as those of embryos) and small pieces of tissues; it preserves glycogen and nuclei and permits brilliant staining, but penetrates slowly, distorts kidney tissue and mitochondria, and does not permit Feulgen stain for DNA.
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Examples: glitazone, GI cocktail, etc.
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