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blue diaper syndrome


Definition: a disorder of tryptophan absorption; excess unabsorbed tryptophan in the intestine is metabolized to indoles and indicans, which are absorbed and lead to excretion of indican in the urine, which is oxidized in the diaper to indigo; patients also have hypercalcemia and nephrocalcinosis.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.