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blocking antibody

 

Definition:

  1. antibody that, in certain concentrations, does not cause precipitation after combining with specific antigen, and that, in this combined state, “blocks” activity of additional antibody added to increase the concentration to a level at which precipitation would ordinarily occur;
  2. the IgG class of immunoglobulin that combines specifically with an atopic allergen but does not elicit a type I allergic reaction, the combined IgG antibody “blocking” available IgE class (reaginic) antibody activity.

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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